Aller au contenu


Accueil > Productions scientifiques

Productions scientifiques

Ouvrages


  • Dominique Barjot et Trang Phan (dir.), Economie et développement durable : héritages historiques et défis actuels au sein du monde francophone, SFHOM, 2016.
     
  • David Cumin, Histoire de la guerre, Paris, Ellipses, 2014.
     
  • David Cumin, Manuel de droit de la guerre, Bruxelles, Larcier/Bruylant, 2014.

Voir tout

Articles


  • [hal-01953249] Cortical drive and thalamic feed-forward inhibition control thalamic output synchrony during absence seizures
    23 décembre 2018
    Behaviorally and pathologically relevant cortico-thalamo-cortical oscillations are driven by diverse interacting cell-intrinsic and synaptic processes. However, the mechanism that gives rise to the paroxysmal oscillations of absence seizures (ASs) remains unknown. Here we report that during ASs in behaving animals, cortico-thalamic excitation drives thalamic firing by preferentially eliciting tonic rather than T-type Ca 2+ channels (T-channels)-dependent burst firing in thalamocortical (TC) neurons, and by temporally framing thalamic output via feed-forward reticular thalamic (NRT)-to-TC neuron inhibition. In TC neurons, overall ictal firing is markedly reduced and bursts rarely occur. Moreover, block of T-channels in cortical and NRT neurons suppresses ASs, but in TC neurons has no effect on seizures or on ictal thalamic output synchrony. These results demonstrate ictal bidirectional cortico-thalamic communications and provide the


Voir tout


Archives ouvertes HAL

Portail des publications scientifiques de l'Université Jean Moulin Lyon 3.
Accéder au portail
Université de Lyon